You might have some luck setting the LD_LIBRARY_PATH before python runs. Note the example below imports the requests package, which spits up the same error. $ /opt/splunk/bin/python Python 2.7.13 (default, Nov 1 2017, 03:43:17) [GCC 5.3.0] on linux2 Type "help", "copyright", "credits" or "license" for more information. >>> import requests >>> ERROR:root:code for hash md5 was not found. [snip] >>> exit() $ export LD_LIBRARY_PATH=/opt/splunk/lib $ /opt/splunk/bin/python Python 2.7.13 (default, Nov 1 2017, 03:43:17) [GCC 5.3.0] on linux2 Type "help", "copyright", "credits" or "license" for more information. >>> import requests >>> Not sure what to do (other than setting os.environ['LD_LIBRARY_PATH'] and spawning a new python process or something equally ugly) if you can only do things within python. ,You might have some luck setting the LD_LIBRARY_PATH before python runs: $ /opt/splunk/bin/python Python 2.7.13 (default, Nov 1 2017, 03:43:17) [GCC 5.3.0] on linux2 Type "help", "copyright", "credits" or "license" for more information. >>> import requests >>> ERROR:root:code for hash md5 was not found. [snip] >>> exit() $ export LD_LIBRARY_PATH=/opt/splunk/lib $ /opt/splunk/bin/python Python 2.7.13 (default, Nov 1 2017, 03:43:17) [GCC 5.3.0] on linux2 Type "help", "copyright", "credits" or "license" for more information. >>> import requests >>> Not sure what to do (other than setting os.environ['LD_LIBRARY_PATH'] and spawning a new python process or something equally ugly) if you can only do things within python. ... View more