Hey Jordan54,
You need to plan your architecture as per your requirements.
Points to consider:
1. Replication factor and Search factor, your indexer sizing will differ accordingly.
2. Replication to be only across site or within site as well.
3. Data indexing will be load balanced across cluster irrespective of site or in the particular site.
Refer the docs below:
http://docs.splunk.com/Documentation/Splunk/7.0.2/Indexer/Multisitearchitecture
http://docs.splunk.com/Documentation/Splunk/7.0.2/Indexer/Multisiteclusters
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