So without knowing the underpinnings of the VMware App csv lookups usage - you could "try" to blacklist that csv file from being replicated by putting it inside the distsearch.conf file under the [replicationBlacklist] section. I say "try" because I don't know for sure if that will break search on the indexers. Also not knowing the format per say, but you can also look inside the csv and prune out old data if it has existed for a long time.
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