Hello,
I had the same issue. Mine turned out to be Postfix storing a huge number of emails in the mail queue due to a real-time alert that didn't have a throttle set. The server was sending out three emails at a time every 70 minutes, and had nearly 600 in the queue. The alert may be gone, but it has already triggered all of the emails.
Check the Postfix mail queue:
postqueue -p
You will likely see a number of undeliverable emails sitting in the queue:
(delivery temporarily suspended: connect to (mailserver)[:4d0:a302:1100::151]:25: Network is unreachable)
Clear the entire queue including deferred emails:
postsuper -d ALL deferred
And that should fix it.
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