Hi @adamhands96,
no you can run a single search:
index=my_index ([ | inputlookup IOC1.csv | rename IP AS src_ip | fields src_ip ] OR [ | inputlookup IOC1.csv | rename Ip AS dest_ip | fields dest_ip ]) NOT ([ | inputlookup IOC2.csv | rename IP AS src_ip | fields src_ip ] OR [ | inputlookup IOC2.csv | rename Ip AS dest_ip | fields dest_ip ])
| ...
Ciao.
Giuseppe
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