I don't see why not since you can use any normal alert action with in ES by running it against the notable index (using the notable macro). You can do this from search too using the Splunk's built-in alert action interface (i.e. you don't have to use ES' Adaptive Response UI if you don't want to).
BTW: this answer assumes that you want to send events via a search and not on an ad-hoc basis. I'm assuming this because I think this would be the more common use-case.