What does these files mean.
In dir /opt/splunk
Did you find these in dispatch directory (/opt/splunk/var/run/splunk/dispatch)? These are search artifacts. whenever you run search (either saved OR adhoc) it created these artifacts on the same node.
when the job expires these artifacts gets deleted.
Whenever search runs it creates search artifacts in $SPLUNK_HOME/var/run/splunk/dispatch
"scheduler__nobody_U0EtSWRlbnRpdHlNYW5hZ2VtZW50" is created by scheduled search in SA-IdentityManagement (decoded from base64 of U0EtSWRlbnRpdHlNYW5hZ2VtZW50)
Another one starting with "rsa_scheduler__nobody_U3BsdW5rX1NBX0NJTQ" is replicated search artifacts for the sched search, "scheduler__nobody_U3BsdW5rX1NBX0NJTQ_..." according to your shclustering replication_factor.
Ophthalmological diseases such as cataract, glaucoma, age-related macular degeneration (AMD), presbyopia, dry eye disease (DED), ocular allergy and others can lead to visual impairment and blindness. Development of therapeutic strategies for ophthalmological diseases requires a comprehensive understanding of the etiology, molecular and anatomical pathogenic mechanisms and natural history of the disease.